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Pipeline >> Overview

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Pipeline Overview

Developing two strong lead compounds: Plecanatide (SP-304) & SP-333 to Treat GI Disorders & Diseases

Plecanatide (SP-304)
A patented drug candidate that targets GC-C receptors in the GI tract. Plecanatide, formerly known as Guanilib, is being developed to treat GI disorders, including chronic constipation and IBS-C.

Plecanatide is currently completing a Phase IIa clinical trial in chronic constipation patients in early 2010.

SP-333
A second-generation Synergy drug candidate that targets GC-C receptors in the GI tract, and is being developed to treat ulcerative colitis.

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