Novel therapeutics from breakthrough research
in gastrointestinal disorders and diseases
Synergy Pharmaceuticals, Inc. (SGYP.OB) is a public, development-stage biopharmaceutical company that develops drugs to treat gastrointestinal (GI) conditions and diseases.
Our patented drug candidates, currently in clinical development, were discovered and developed in-house by Synergy scientists.
The company has its headquarters in New York City and also operates a research laboratory in Doylestown, PA that supports Synergy’s drug development programs.
Synergy’s drug development program and patent estate are based on a class of synthetic peptides designed to mimic uroguanylin, a human hormone that regulates intestinal fluid transport.
Synergy has a lead drug, Plecanatide (SP-304), in clinical development to treat chronic constipation (CC) and constipation-predominant irritable bowel syndrome (IBS-C). A second drug, SP-333, is in pre-clinical development for GI diseases.
Lead Drug Development Program: Plecanatide(SP-304)
The market opportunity for gastrointestinal therapeutics was recently valued at around $50 BN in 2008. The US market which comprises almost 40% of the estimated global market is worth almost $19 BN.
Chronic constipation and IBS-C have a wide prevalence, affecting up to 15% and 20% of the population respectively. More than 100 million people worldwide suffer from these conditions.
Gastrointestinal Disorders (GI) & Diseases
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